AKT http://en.wikipedia.org/wiki... , NF-κB http://en.wikipedia.org/wiki... , 9 -28 sort The multiple roles of the innate immune system in the regulation of apoptosis and inflammation in the brain. http://www.ncbi.nlm.nih.gov/pubmed... , 2 -10 http://friendfeed.com/citizen... , 7 -24 http://www.usnews.com/news... 12 -16 inflammation http://friendfeed.com/citizen... 12 -29 http://www.scientificamerican.com/article... - Thomas Page

in pink box sort Vitamin D receptor as a master regulator of the c-MYC/MXD1 network http://www.pnas.org/content... C-myc mRNA - Wikipedia, the free encyclopedia , C-myc mRNA is a type of mRNA that serves as a template for the MYC protein which is implicated in the rapid growth of cancer cells. This mRNA is a topic of ongoing research to investigate the viability of preventing cancer growth by cleaving or degrading the c-myc mRNA.[1] http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://www.wikigenes.org/e... http://www.wikigenes.org/e... http://www.pnas.org/content... ( cancer , NF-κB , IGF-1 , AKT http://friendfeed.com/citizen... ) , 1 -4 http://articles.mercola.com/sites... http://en.wikipedia.org/wiki... http://articles.mercola.com/sites... http://www.wikigenes.org/e... http://en.wikipedia.org/wiki... http://lipidlibrary.aocs.org/lipids... http://www.nugowiki.org/index... http://www.cyberlipid.org/sterols... http://www.cyberlipid.org/sterols... http://stephanie-on-health.blogspot.com/2011... http://paleohacks.com/questio... , 1 -5 ? http://en.wikipedia.org/wiki... ? , 2 -5 sort Tumor Cells Exhibit a Bioelectric Signature mRNAs (messenger RNA) encoding well-recognized human oncogenes Gli1, KrasG12D, and Xrel3. http://www.sciencedaily.com/release... 4 -2 http://articles.mercola.com/sites... - Thomas Page

PI3K/AKT/mTOR pathway http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... , 2 -5 sort Cannabinoid receptor type 2 http://en.wikipedia.org/wiki... - Thomas Page

HIF activity is involved in angiogenesis required for cancer tumor growth, so HIF inhibitors such as phenethyl isothiocyanate and Acriflavine[22] are under investigation for anti-cancer effects.[23][24][25] ~ The results of a recently published study have numerous implications for a number of pathologies where NF-κB and HIF-1 are deregulated, including rheumatoid arthritis and cancer. Therefore, it is thought that understanding the cross talk between these two key transcription factors, NF-κB and HIF, will greatly enhance the process of drug development.[14] http://en.wikipedia.org/wiki... [ phenethyl isothiocyanate http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... Isothiocyanates http://en.wikipedia.org/wiki... ( Horseradish http://www.theepicentre.com/Spices... , http://en.wikipedia.org/wiki... , Wasabi http://en.wikipedia.org/wiki... The chemical in wasabi that provides for its initial pungency is the volatile allyl isothiocyanate, which is produced by hydrolysis of natural rhizome thioglucosides (conjugates of the sugar glucose, and sulfur-containing organic compounds); the hydrolysis reaction is catalyzed by myrosinase and occurs on when the enzyme is released on cell rupture caused by maceration—e.g., grating—of the plant's rhizome.[7][8][9] The unique flavor of wasabi is a result of complex chemical mixtures from the broken cells of the rhizome, including those resulting from the hydrolysis—glucose, and other methylthioalkyl isothiocyanates:[10][11][12] 6-methylthiohexyl isothiocyanate, 7-methylthioheptyl isothiocyanate, and 8-methylthiooctyl isothiocyanate. Research has shown that such isothiocyanates inhibit microbe growth, perhaps with implications for preserving food against spoilage and suppressing oral bacterial growth.[13 , ) [ Mustard [ Watercress http://en.wikipedia.org/wiki... Many benefits from eating watercress are claimed, such as that it acts as a stimulant, a source of phytochemicals and antioxidants, a diuretic, an expectorant, and a digestive aid.[7] It also appears to have antiangiogenic cancer-suppressing properties; it is widely believed to help defend against lung cancer.[8][9][10][11] A 2010 study conducted by the University of Southampton found that consumption of watercress may also inhibit the growth of breast cancer.[12] The content of phenethyl isothiocyanate (PEITC) in watercress inhibits HIF, which can inhibit angiogenesis. [ http://en.wikipedia.org/wiki... EPO Erythropoietin http://en.wikipedia.org/wiki... , - Thomas Page

difference between Apoptosis and Angiogenesis? The Hallmarks of Cancer http://en.wikipedia.org/wiki... sort https://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... 5 -28 What Science Knows about Cancer http://www.thegreatcourses.com/tgc... sort http://www.thegreatcourses.com/tgc... , 6 -9 http://en.wikipedia.org/wiki... http://www.nytimes.com/2010... http://www.seattlepi.com/enterta... , 11 -7 http://m.theatlantic.com/health... The War on Cancer: From Nixon Until Now http://www.youtube.com/watch... http://www.nature.com/nature... http://www.scientificamerican.com/article... 12 -18 http://bigthink.com/ideafee... - Thomas Page

Apoptosis is characterized by well defined cytological and molecular events including a change in the refractive index of the cell, cytoplasmic shrinkage, nuclear condensation and cleavage of DNA into regularly sized fragments.[2] Cells in culture that are undergoing apoptosis eventually undergo secondary necrosis. They will shut down metabolism, lose membrane integrity and lyse.[2][3] http://en.wikipedia.org/wiki... , 6 -13 JAK-STAT signaling pathway The JAK-STAT pathway is evolutionarily conserved, from slime molds and worms to mammals (but not fungi or plants). Disrupted or dysregulated JAK-STAT functionality (which is usually by inherited or acquired genetic defects) can result in immune deficiency syndromes and cancers.[1] http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... 2 -1 http://friendfeed.com/citizen... - Thomas Page

Autophagy http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... Short-term fasting induces profound neuronal autophagy. http://www.ncbi.nlm.nih.gov/pubmed... , 9 -25 http://friendfeed.com/mercola... sort http://www.perlhealth.com/about-d... http://www.drperlmutter.com/ http://www.doctoroz.com/medadvi... http://www.webmd.com/vitamin... , 10 -12 http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... - Thomas Page

http://www.nytimes.com/2014... T cells 9 -5 https://friendfeed.com/citizen... 12 -24 sort http://en.wikipedia.org/wiki... - Thomas Page

9 -5 http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... [ http://www.iflscience.com/health-... http://www.nature.com/ncomms... 9 -7 http://medicalxpress.com/news... - Thomas Page

how-exercise-changes-our-dna http://well.blogs.nytimes.com/2014... < 12 -19 ] http://www.sciencedirect.com/science... Highlights • Exercise alters the gene expression pattern in multiple tissues. • Regular exercise can modify the genome-wide DNA methylation http://en.wikipedia.org/wiki... pattern in humans. • Regular exercise could potentially affect metabolic phenotypes and risk of disease. Regular exercise has numerous health benefits, for example, it reduces the risk of cardiovascular disease and cancer. It has also been shown that the risk of type 2 diabetes can be halved in high-risk groups through nonpharmacological lifestyle interventions involving exercise and diet. Nevertheless, the number of people living a sedentary life is dramatically increasing worldwide. Researchers have searched for molecular mechanisms explaining the health benefits of regular exercise for decades and it is well established that exercise alters the gene expression pattern in multiple tissues. However, until recently it was unknown that regular exercise can modify the genome-wide DNA methylation pattern in humans. This review will focus on recent progress in the field of regular exercise and epigenetics. 5 -12 http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... Cress http://en.wikipedia.org/wiki... sort http://en.wikipedia.org/wiki... ? 5 -16 http://expandedconsciousness.com/2014... - Thomas Page

quantity of neuro endocrine control-ability interaction? https://friendfeed.com/citizen... [ sort Freedom from the BORG - REPTILIANS ? - Thomas Page

Intermittent Movement Benefits Your Health. Here’s How to Get More of It into Your Work Day http://fitness.mercola.com/sites... it appears that temporary vigorous exercise can't even compensate for the damage incurred by prolonged daily sitting! In fact, it's becoming increasingly clear that staying active—and by that I mean engaging in virtually any physical movement—as much as possible, throughout the day, is critical for health and longevity. It even appears to be more important, in the big scheme of things, than a regularly scheduled fitness routine... locomotion https://friendfeed.com/citizen... sort http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... [[[[ 1 -2 Neurobiological effects of physical exercise http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://m.wikihow.com/Jog-You... [ Eureka_effect http://en.wikipedia.org/wiki... 7 -30 BDNF http://en.wikipedia.org/wiki... - Thomas Page

9 -25 sort http://en.wikipedia.org/wiki... [ 2 -23 http://www.cdc.gov/cancer... - Thomas Page

Sort Heparan_sulfate http://en.wikipedia.org/wiki... Betaglycan http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... Proteoglycan http://en.wikipedia.org/wiki... - Thomas Page

JAK-STAT_signaling_pathway http://en.wikipedia.org/wiki... http://en.m.wikipedia.org/wiki... http://en.wikibooks.org/w... [ During development of the central nervous system, FGFs http://en.wikipedia.org/wiki... play important roles in neurogenesis, axon growth, and differentiation. FGFs are also important for maintenance of the adult brain. Thus, FGFs are major determinants of neuronal survival both during development and during adulthood.[24] Adult neurogenesis within the hippocampus e.g. depends greatly on FGF-2. In addition, FGF-1 and FGF-2 seem to be involved in the regulation of synaptic plasticity and processes attributed to learning and memory, at least in the hippocampus.[citation needed] Most FGFs are secreted proteins that bind heparan sulfates and can, therefore, be caught up in the extracellular matrix of tissues that contain heparan sulfate proteoglycans. This local action of FGF proteins is classified as paracrine signalling, most commonly through the JAK-STAT signaling pathway or the Receptor tyrosine kinase (RTK) pathway. [[ FGF1 http://en.wikipedia.org/wiki... [[[ http://en.wikipedia.org/wiki... [[[[ see above http://en.wikipedia.org/wiki... 7 -28 http://www.salk.edu/news... http://www.nature.com/nature... - Thomas Page

. - Thomas Page

12 -26 http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... Histamine http://en.wikipedia.org/wiki... 12 -30 sort https://friendfeed.com/citizen... - Thomas Page

. - Thomas Page

12 -29 Wearing The Cold Shoulder vest http://coldshoulderweightloss.com/ activates a type of tissue called brown fat http://www.theatlantic.com/magazin... http://io9.com/a-crazy... fits how? > Sirtuin http://en.wikipedia.org/wiki... - Thomas Page

12 -26 Emu_oil http://en.wikipedia.org/wiki... Rodney - Emu http://en.wikipedia.org/wiki... https://www.consumerhealthdigest.com/topical... http://supplement-geek.com/austral... Blue Emu 3 -5 https://friendfeed.com/citizen... - Thomas Page

angiogenesis Relates to how? > http://en.wikipedia.org/wiki... Brown_adipose_tissue http://en.wikipedia.org/wiki... sort https://friendfeed.com/citizen... disease https://friendfeed.com/citizen... 12 -24 http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... - Thomas Page

12 -23 sort Habits of Consciousness, Loops [ Consciousness synchronization with wetware, software, hardware. and Habitat. [[ Actionable Action , Habitat - Self , Now { Time Horizons - Thomas Page

. - Thomas Page

. - Thomas Page

. - Thomas Page

. - Thomas Page

Inflammatory_cascade http://en.wikipedia.org/wiki... Inflammasomes activation and signaling overview.png http://en.wikipedia.org/wiki... - Thomas Page

Inflammatory_cascade http://en.wikipedia.org/wiki... Inflammasomes activation and signaling overview.png http://en.wikipedia.org/wiki... - Thomas Page