Learning and memory are attributed to changes in neuronal synapses, thought to be mediated by long-term potentiation http://en.wikipedia.org/wiki... and long-term depression http://en.wikipedia.org/wiki... . ] http://en.wikipedia.org/wiki... [[ http://en.wikipedia.org/wiki... - Thomas Page

7 -16 sort Methylation#In_biology http://en.wikipedia.org/wiki... [ http://en.wikipedia.org/wiki... In neuroscience, glutamate is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and retaining memory.[4] http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... 7 -26 http://en.wikipedia.org/wiki... - Thomas Page

8 -9 Brain-computer_interface http://en.wikipedia.org/wiki... - Thomas Page

1 -27 http://en.wikipedia.org/wiki... Hassabis then left the games industry, switching to cognitive neuroscience, in order to get back to his lifelong passion of developing artificial intelligence technology. Working in the field of autobiographical memory and amnesia he authored several highly cited and influential papers, including his most prominent work to date, which was published in the Proceedings of the National Academy of Sciences in early 2007.[11] It demonstrated that patients with damage to their hippocampus, known to cause amnesia, were also unable to imagine themselves in new experiences. Importantly this established a link between the constructive process of imagination and the reconstructive process of episodic memory recall. Based on these findings and a follow-up fMRI study,[12] Hassabis developed his ideas into a new theoretical account of the episodic memory system identifying scene construction, the generation and online maintenance of a complex and coherent scene, as a key process underlying both memory recall and imagination.[13] This work was widely covered in the mainstream media[14] and was listed in the top 10 scientific breakthroughs of the year (at number 9) in any field by the journal Science.[15] Recently some of Hassabis' findings and interpretations have been challenged by other researchers. A paper by Larry R. Squire and colleagues [16] reported a dissociation between hippocampal lesions and imagination deficits as well as between amnesia and imagination deficits. Furthermore, Squire and colleagues questioned whether the lesions of the patients tested by Hassabis and colleagues were restricted to the hippocampus. However, many independent patient studies have now confirmed the original findings,[17] although the debate is ongoing.[18] http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://www.nature.com/neuro... http://en.wikipedia.org/wiki... http://www.thenarrativebreakdown.com/topics... http://en.wikipedia.org/wiki... http://www.jneurosci.org/content... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://www.npr.org/2012... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://www.oecd.org/edu... http://www.senseaboutscience.org/blog... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... [[[[[[ 2 -2 What is intelligence? How can we formalise machine intelligence? Solomonoff Induction: a universal prediction system. AIXI: Hutter's universal artificial intelligence. MC-AIXI: a computable approximation of AIXI. Can the brain tell us anything useful for building an AI? Is building a super intelligent machine a good idea? http://hplusmagazine.com/2014... http://en.wikipedia.org/wiki... - Thomas Page

1 -28 Context-dependent_memory http://en.wikipedia.org/wiki... Think_Gum http://en.wikipedia.org/wiki... - Thomas Page

1 -21 Prospective_memory http://en.wikipedia.org/wiki... - Thomas Page

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3 -24 sort http://time.com/35551... - Thomas Page

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8 -28 sort http://www.the-scientist.com/... WIKIMEDIA, MARK HARKIN Researchers have made mice enjoy spending time in a place they once feared using light-dependent manipulations of the animals’ neurons, according to a study published today (August 27) in Nature. This optogentically controlled memory reversal appears to be driven by altered connections between hippocampal neurons—which encode “where” memories—and amygdala neurons—which code for either positive or negative emotions, but not both—MIT researchers have found. “It is an exciting advance in our understanding of the malleability of memory,” said Elizabeth Phelps, a professor of psychology and neural science at New York University who was not involved in the work. “They are giving us some more insight into the complex representation of aversive and appetitive memories and when and how they [change].” Memories are created and stored in multiple areas of the brain. The amygdala, for example, processes information relating to whether something is good or bad, pleasurable or scary, and the hippocampus stores information about particular places and events, explained Richard Morris, a professor of neuroscience at the University of Edinburgh who also did not participate in the study. “But if the amygdala and hippocampus talk to each other through fiber pathways, then you . . . remember a particular place and—because the amygdala neurons are doing their thing—you also remember it’s a good place,” said Morris. Such good or bad feelings, or the emotional valence, linked to places and events enable animals to avoid dangers—so-called aversive behavior—and seek out benefits—appetitive behavior. But emotional valence isn’t rigid. Circumstances change and places that an animal once viewed as happy, safe, or warm, can become scary, unpleasant, or upsetting. Susumu Tonegawa, a professor of biology and neuroscience at MIT, wanted to understand the physiological mechanisms behind this change in emotional valence. To find out, he and his colleagues used an optogenetic technique that, with a light-activated protein, labels only those neurons that fire during the formation of a specific new memory. The resulting light-inducible memory-associated cells can then be reactivated with lasers “at will,” explained Roger Redondo, a postdoctoral scientist in Tonegawa’s laboratory and a lead author of the new study. The team used the technique to label neurons in the amygdala or hippocampus that were activated as male mice learned to fear a particular location, where they received electric shocks to the feet. The researchers then housed each fear-conditioned male mouse with female mice—a pleasant experience—while reactivating their now light-inducible neurons in the hippocampus or amygdala. When the amygdala-reactivated mice were returned to the location they had learned to fear, the animals froze in apparent anticipation of an electric shock, indicating that they still remembered the place was dangerous. When the hippocampus-reactivated mice were returned, however, they were no longer fearful—their memories of the place had become pleasant thanks to the neurons having been reactivated in the presence of the female mice. The researchers also performed the reverse experiment, giving male mice access to females in the original location and later reactivating their memory-associated neurons while administering electric shocks. Again, the mice in which amygdala neurons had been reactivated remained happy in the original location, while the mice in which hippocampal neurons had been reactivated became fearful. “The take-home message is that within the hippocampus there is a representation that can be flexibly switched to have an appetitive or aversive meaning, but within the amygdala there appear to be appetitive or aversive circuits that cannot switch their meaning so easily,” said Daniel Salzman, a professor of neuroscience and psychiatry at Columbia University in New York who was not involved in the work. The inability of the amygdala circuits to change their valence is thought to be because these neurons either code for “good” or “bad” but not both, said Redondo. Thus, reactivating the labeled amygdala neurons would only have reiterated the original emotion. Indeed, in animals in which hippocampal reactivation had changed their emotions, different cells in the amygdala were activated. “Basically, the [hippocampal] neurons are now plugged to another set of neurons in the amygdala,” explained Redondo. Changing the emotional valence of a memory is a clinical goal for patients who suffer from conditions such as phobias or post-traumatic stress disorder. Indeed, “associations to emotions can be so strong that they impair normal life,” said Redondo. While optogenetic manipulation of people’s memories may be a long way off, “if we did have a better understanding, mechanistically, about how different emotional behaviors work in the brain, then we would be able to perhaps target even better treatment strategies than are currently available,” said Salzman. R.L. Redondo et al., “Bidirectional switch of the valence associated with a hippocampal contextual memory engram,” Nature, doi:10.1038/nature13725, 2014. - Thomas Page

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1 -13 sort Art_diary http://en.wikipedia.org/wiki... http://www.stevepavlina.com/the-jou... http://www.davidrm.com/ http://www.stevepavlina.com/blog... http://www.lifehack.org/article... five-best-journaling-tools http://lifehacker.com/5246819... http://psychcentral.com/lib... http://tinybuddha.com/blog... - Thomas Page

Diaries http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... [ Journaling , Reflective writing http://en.wikipedia.org/wiki... Art Journal http://www.wikihow.com/Use-an-... sort ? Structured Journal http://www.structuredjournal.com/ Time use research http://en.wikipedia.org/wiki... - Thomas Page

3 -19 writing tools brain amplifiers knowledge management ? - Thomas Page

3 -1 Emotivism http://en.wikipedia.org/wiki... Reconstructive_memory http://en.wikipedia.org/wiki... The_Meisner_technique http://en.wikipedia.org/wiki... Affective_memory http://en.wikipedia.org/wiki... How to Optimize Your Brain: Why Refining Emotional Recall is the Secret to Better Memory http://www.brainpickings.org/index... 1 -3 Acting http://friendfeed.com/citizen... - Thomas Page

7 -27 Neurobiological effects of physical exercise http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://m.wikihow.com/Jog-You... - Thomas Page

Psychomagnotheric Slime (also known as Mood Slime and Psycho-Reactive Slime) Psychomagnatheric Ectoplasm http://ghostbusters.wikia.com/wiki... 3 -8 http://www.esquire.com/blogs... - Thomas Page

5 -29 sort remembrance recall http://dictionary.reference.com/browse... 12 -28 Blackbox http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... - Thomas Page

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What matters in life is not what happens to you but what you remember and how you remember it. Gabriel Garcia Marquez http://en.wikiquote.org/wiki... http://www.brainyquote.com/quotes... http://en.wikipedia.org/wiki... http://www.policymic.com/article... [[ 4 -27 "Life is 10% of what happens to me and 90% of how I react to it.” – John Maxwell - Thomas Page

1 -3 Attention_versus_memory_in_prefrontal_cortex - Thomas Page

Gratitude , Forgiveness http://en.wikipedia.org/wiki... http://m.wikihow.com/Forgive http://www.psychologytoday.com/basics... http://www.mayoclinic.org/healthy... - Thomas Page

1 -2 misc How to be a Mensch http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... "better human being" ] [ feeling lamentations for auld lang syne , while the present could use attention ] [ absolution http://en.wikipedia.org/wiki... penance ?? [ ground hogs day - temporal crossfeed ? , http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... Dialectical_behavior_therapy http://en.wikipedia.org/wiki... 12 step sharpen the saw ?? Done ? Attention_versus_memory_in_prefrontal_cortex ???? [ http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... [[[[[[[[[ http://en.wikipedia.org/wiki... - Thomas Page

Memorial - Thomas Page

9 -11 Memory_and_aging http://en.wikipedia.org/wiki... - Thomas Page

1 -2 edit } Auld Lang Syne ,The song begins by posing a rhetorical question as to whether it is right that old times be forgotten, and is generally interpreted as a call to remember long-standing friendships [ Blade Runner tears in the Rain [[ Blue Eyes Crying in the Rain http://youtu.be/JA644rSZX1A {{{{{{ The song's Scots title may be translated into standard English as "old long since", or more idiomatically, "long long ago",[4] "days gone by" or "old times". Consequently "For auld lang syne", as it appears in the first line of the chorus, might be loosely translated as "for (the sake of) old times". Auld_Lang_Syne http://en.wikipedia.org/wiki... 1 -21 sort List_of_number-one_adult_contemporary_singles_of_1982_(U.S.) - Thomas Page

This chart takes the milestones of the average American life — everything from becoming eligible for a driver's license to getting (and leaving) a first job — and plots them all out into weeks. http://io9.com/chart-r... http://reasonandmeaning.com/2014... Memory of events in a week? Jogging the memory? [ 20 yrs of scoolin and they put you on the swing shift ~ god knows when but your doin it again ~ [[ Avalons and Camalots ... Woebegons [[[[ Man-hours spent how? Weekly? ( Jared Diamond on how cultures spend time? [[[[[[ Speech Ways: "Conventional patterns of written and spoken language; pronunciation, vocabulary, syntax and grammar." Building Ways: "Prevailing forms of vernacular architecture and high architecture, which tend to be related to one another." Family Ways: "The structure and function of the household and family, both in ideal and actuality." Marriage Ways: "Ideas of the marriage-bond, and cultural processes of courtship, marriage and divorce." Gender Ways: "Customs that regulate social relations between men and women." Sex Ways: "Conventional sexual attitudes and acts, and the treatment of sexual deviance." Child-Rearing Ways: "Ideas of child nature and customs of child nurture." Naming Ways: "Onomastic customs including favoured forenames and the descent of names within the family." Age Ways: "Attitudes towards age, experiences of aging and age relationships." Death Ways: "Attitudes towards death, mortality rituals, mortuary customs and mourning practices." Religious Ways: "Patterns of religious worship, theology, ecclesiology and church architecture." Magic Ways: "Normative beliefs and practices concerning the supernatural." Learning Ways: "Attitudes toward literacy and learning, and conventional patterns of education." Food Ways: "Patterns of diet, nutrition, cooking, eating, feasting and fasting." Dress Ways: "Customs of dress, demeanor, and personal adornment." Sport Ways: "Attitudes toward recreation and leisure; folk games and forms of organized sport." Work Ways: "Work ethics and work experiences; attitudes toward work and the nature of work." Time Ways: "Attitudes toward the use of time, customary methods of time keeping, and the conventional rhythms of life." Wealth Ways: "Attitudes towards wealth and patterns of its distribution." Rank Ways: "The rules by which rank is assigned, the roles which rank entails, and the relations between different ranks." Social Ways: "Conventional patterns of migration, settlement, association and affiliation." Order Ways: "Ideas of order, ordering institutions, forms of disorder, and treatment of the disorderly." Power Ways: "Attitudes toward authority and power; patterns of political participation." Freedom Ways: "Prevailing ideas of liberty and restraint, and libertarian customs and institutions." - Thomas Page

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1 -13 sort edit GNH ? [{( -- they are about cherished memories, shared adventures, small kindnesses and acts of generosity, lifelong passions, and the things that made us laugh. )}] pstp psy sup Job Description Grows for Our Utility Hormone http://www.nytimes.com/2011... , http://www.biopsychiatry.com/seroton... , Seratonin: The chemistry of Well-Being http://www.angelfire.com/hi... , 1 -12 The Good Drug Guide http://www.biopsychiatry.com/ [ Well-Being http://en.wikipedia.org/wiki... http://en.wikipedia.org/wiki... 1 -10 edit> Thrive }}} Arianna likened our drive for money and power to two legs of a three-legged stool. They may hold us up temporarily, but sooner or later we're going to topple over. We need a third leg -- a third metric for defining success -- to truly thrive. That third metric, she writes in Thrive, includes our well-being, our ability to draw on our intuition and inner wisdom, our sense of wonder, and our capacity for compassion and giving. As Arianna points out, our eulogies celebrate our lives very differently from the way society defines success. They don't commemorate our long hours in the office, our promotions, or our sterling PowerPoint presentations as we relentlessly raced to climb up the career ladder. They are not about our resumes -- they are about cherished memories, shared adventures, small kindnesses and acts of generosity, lifelong passions, and the things that made us laugh. [[[[[[ Measurement of thrive method- metric ? GNH ? [{( -- they are about cherished memories, shared adventures, small kindnesses and acts of generosity, lifelong passions, and the things that made us laugh. - Thomas Page

Memory for the future http://en.wikipedia.org/wiki... [ Event-based vs. Time-based prospective memory http://en.wikipedia.org/wiki... [[ Attention_versus_memory_in_prefrontal_cortex http://en.wikipedia.org/wiki... - Thomas Page

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Grandpa on Hee Haw, Life is Stranger than fiction. [ The Culhanes http://en.wikipedia.org/wiki... [[ 12 -30 https://friendfeed.com/citizen... 2 -15 misery song on Hee haw [ desolation [[[ GLOOM, DESPAIR AND AGONY ON ME From the TV Show "Hee-Haw" (1969 -1992) Buck Owens & Roy Clark Gloom, despair, and agony on me Deep, dark depression, excessive misery If it weren't for bad luck, I'd have no luck at all Gloom, despair, and agony on me We figured she was rich, loaded to the hilt And we figured she had class like the Vanderbilts 'Cause we had heard for years how she was so well reared How was we to know they meant the way she was built Gloom, despair, and agony on me Deep, dark depression, excessive misery If it weren't for bad luck, I'd have no luck at all Gloom, despair, and agony on me - Thomas Page

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Rosebud, It's a Wonderfull Life -Mr Smith, Dickens } tidings of comfort and joy, may nothing you dismay, and Irish Blessings https://friendfeed.com/citizen... to boot http://dictionary.reference.com/browse... ... - Thomas Page