Markus Covert et al. used data from more than 900 scientific papers to account for every molecular interaction that takes place in the life cycle of Mycoplasma genitalium which contains the smallest genome of any free-living organism: 525 genes. Complex phenotypes can be modeled by integrating cell processes into a single model. Unobserved cellular behaviors, new biological processes and parameters are predicted by this bio-CAD model -- including in vivo rates of protein-DNA association and an inverse relationship between the durations of DNA replication initiation and replication. \\ A giant step for Artificial Life! - Adriano