[...] Section 1 describes the importance of linking biology to models, and why the syntax of those links is vital to their usefulness. Section 2 describes the technology used to implement Saint, while Section 3 focuses on how Saint retrieves model annotation and how it can be used to pick and choose the annotation to keep. Section 4 provides practical examples of annotating models using Saint. Finally, Section 5 describes the future plans for Saint, the collaborations that have been developed, and how Saint can be used with rule-based mediation (see Chapter 5). [...] - Allyson Lister